Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 4/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2710843 | 1.00 | PLA2G2A (0.56) | PLA2G2APTPN11MAOAMAOBTP53 | |
| SCHEMBL2710789 | 1.00 | PLA2G2A (0.56) | PLA2G2APTPN11MAOAMAOBTP53 | |
| SCHEMBL7089888 | 0.94 | PTPN11 (0.48) | PLA2G2APTPN11MAOAMAOBTP53 | |
| SCHEMBL28280526 | 0.83 | PTPN11 (0.62) | PLA2G2APTPN11MAOAMAOBTP53 | |
| SCHEMBL28870271 | 0.83 | PTPN11 (0.62) | PLA2G2APTPN11MAOAMAOBTP53 | |
| SCHEMBL5095051 | 0.83 | PLA2G2A (0.59) | PLA2G2APTPN11TP53TSHRPLA2G4B | |
| SCHEMBL5090283 | 0.83 | PLA2G2A (0.59) | PLA2G2APTPN11TP53TSHRPLA2G4B | |
| SCHEMBL11049569 | 0.83 | PLA2G2A (0.59) | PLA2G2APTPN11TP53TSHRPLA2G4B | |
| SCHEMBL23748612 | 0.81 | PLA2G2A (0.56) | PLA2G2APTPN11TP53TSHRPLA2G4B | |
| SCHEMBL13162398 | 0.79 | MAOA (0.59) | PTPN11MAOAMAOBTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144458-A1 | Novel amphiphilic polymeric materials | UNIVERSITY OF MASSACHUSETTS, A MASSACHUSETTS CORPORATION | 2003-07-31 | — | — | US | disclosed |
| US-6521736-B2 | Can be used in development of physiologically stable, non-leaking, non-immunogenic, efficacious and safe targetable drug delivery systems e.g., for delivery of anti-HIV or anticancer drugs | UNIVERSITY OF MASSACHUSETTS | 2003-02-18 | — | — | US | disclosed |
| US-20020099164-A1 | Novel amphiphilic polymeric materials | UNIVERSITY OF MASSACHUSETTS | 2002-07-25 | — | — | US | disclosed |