Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 15/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094385 | 0.84 | IDO1 (0.48) | RORCIDO1GSK3BDYRK1A | |
| SCHEMBL7087668 | 0.76 | IDO1 (0.39) | RORCIDO1ALDH1A1GSK3BDYRK1A | |
| SCHEMBL7095527 | 0.76 | IDO1 (0.44) | IDO1 | |
| SCHEMBL7092213 | 0.75 | IDO1 (0.39) | IDO1GSK3BDYRK1A | |
| SCHEMBL7210392 | 0.74 | IDO1 (0.52) | RORCIDO1ALDH1A1 | |
| SCHEMBL6556599 | 0.74 | IDO1 (0.44) | IDO1GSK3BDYRK1A | |
| SCHEMBL6995025 | 0.73 | CSF1R (0.38) | RORCALDH1A1 | |
| SCHEMBL15648081 | 0.70 | RORC (0.52) | RORC | |
| SCHEMBL7095009 | 0.69 | KDM4E (0.34) | ALDH1A1 | |
| SCHEMBL16460357 | 0.68 | RORC (0.46) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322635-A1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024682-A1 | FARNESYL TRANSFERASE INHIBITING QUINOLINE AND QUINAZOLINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-03-28 | — | — | WO | disclosed |