SCHEMBL7089980

SCHEMBL7089980

CC(C)(c1ccccc1)c1cc(-c2ccccc2)cc(C(=O)O)c1O.[Zn]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 0.54
AKR1C2 P52895 7/20 0.53
AKR1C1 Q04828 7/20 0.53
AKR1C3 P42330 2/20 0.53
AKR1C4 P17516 1/20 0.53
PTPN6 P29350 3/20 0.51
PTPN2 P17706 2/20 0.51
ACMSD Q8TDX5 3/20 0.45
HNF4A P41235 2/20 0.45
MCL1 Q07820 2/20 0.45
DHFR P00374 1/20 0.45
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
ALDH1A1 P00352 1/20 0.39
ESR1 P03372 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5145560 0.98 PTPN1 (0.55) PTPN1AKR1C2AKR1C1AKR1C3AKR1C4
Zinc Ion SCHEMBL7089975 0.86 PTPN1 (0.41) PTPN1AKR1C2AKR1C1AKR1C3AKR1C4
SCHEMBL7084776 0.85 ESR1 (0.44) PTPN1AKR1C2AKR1C1AKR1C3AKR1C4
SCHEMBL8373991 0.84 PTPN1 (0.60) PTPN1AKR1C2AKR1C1AKR1C3AKR1C4
SCHEMBL11771849 0.84 CSNK2A1 (0.41) PTPN1AKR1C2AKR1C1MCL1ALDH1A1
Water SCHEMBL9852463 0.84 ESR1 (0.43) PTPN1AKR1C2AKR1C1AKR1C3AKR1C4
SCHEMBL1129729 0.83 ESR1 (0.46) PTPN1AKR1C2AKR1C1AKR1C3AKR1C4
SCHEMBL3019692 0.82 CSNK2A1 (0.42) PTPN1AKR1C2AKR1C1MCL1ALDH1A1
Water SCHEMBL9852464 0.82 ESR1 (0.44) PTPN1AKR1C2AKR1C1AKR1C3AKR1C4
SCHEMBL9615388 0.82 NR5A2 (0.45) PTPN1AKR1C2AKR1C1MCL1RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030191023-A1 Thermosensitive recording material FUJI PHOTO FILM CO., LTD. 2003-10-09 US disclosed