Zinc Ion

Zinc Ion

SCHEMBL7089975

CC(C)(c1ccccc1)c1cc(-c2ccccc2)cc(C(=O)[O-])c1O.CC(C)(c1ccccc1)c1cc(-c2ccccc2)cc(C(=O)[O-])c1O.[Zn+2]

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.41
AKR1C2 P52895 4/20 0.40
AKR1C1 Q04828 4/20 0.40
AKR1C4 P17516 1/20 0.40
AKR1C3 P42330 1/20 0.40
PTPN2 P17706 1/20 0.39
PTPN6 P29350 1/20 0.39
ALDH1A1 P00352 1/20 0.37
ESR1 P03372 1/20 0.37
CYP3A4 P08684 1/20 0.37
ESR2 Q92731 1/20 0.37
ACMSD Q8TDX5 2/20 0.36
DHFR P00374 1/20 0.36
HNF4A P41235 1/20 0.36
MCL1 Q07820 1/20 0.36
CNR1 P21554 3/20 0.36
CNR2 P34972 3/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
RXRA P19793 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL9495956 0.87 CA1 (0.47) PTPN1AKR1C2AKR1C1AKR1C4AKR1C3
SCHEMBL5145560 0.87 PTPN1 (0.55) PTPN1AKR1C2AKR1C1AKR1C4AKR1C3
SCHEMBL7089980 0.86 PTPN1 (0.54) PTPN1AKR1C2AKR1C1AKR1C4AKR1C3
Zinc Ion SCHEMBL7089336 0.86 ESR1 (0.42) ALDH1A1ESR1CYP3A4ESR2CNR1
Zinc Ion SCHEMBL11771848 0.84 ALDH1A1 (0.38) ALDH1A1ESR1CYP3A4ESR2CNR1
Water SCHEMBL9852465 0.84 ESR1 (0.41) ALDH1A1ESR1CYP3A4ESR2CNR1
SCHEMBL9700994 0.83 ALDH1A1 (0.42) ALDH1A1ESR1CYP3A4ESR2CNR1
SCHEMBL11758522 0.82 ALDH1A1 (0.38) ALDH1A1ESR1CYP3A4ESR2CNR1
Zinc Ion SCHEMBL7089200 0.79 SHBG (0.36) ALDH1A1ESR1CYP3A4ESR2CYP2C9
Zinc Ion SCHEMBL7090677 0.78 PTPN1 (0.44) PTPN1AKR1C2AKR1C1AKR1C3PTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030191023-A1 Thermosensitive recording material FUJI PHOTO FILM CO., LTD. 2003-10-09 US disclosed