Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 5/20 | 0.67 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945261 | 1.00 | OXTR (0.67) | OXTRAVPR1AALDH1A1LMNAHPGD | |
| SCHEMBL7090117 | 1.00 | OXTR (0.67) | OXTRAVPR1AALDH1A1LMNAHPGD | |
| SCHEMBL4944228 | 0.87 | OXTR (0.73) | OXTRAVPR1ALMNATSHRKMT2A | |
| SCHEMBL4942261 | 0.84 | OXTR (0.67) | OXTRAVPR1AALDH1A1LMNAHPGD | |
| SCHEMBL4945310 | 0.83 | ALDH1A1 (0.48) | OXTRALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4943162 | 0.83 | ALDH1A1 (0.48) | OXTRALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL4939162 | 0.83 | OXTR (0.73) | OXTRAVPR1AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4944329 | 0.83 | OXTR (0.73) | OXTRAVPR1AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4943696 | 0.82 | OXTR (0.72) | OXTRAVPR1ALMNAHPGDKMT2A | |
| SCHEMBL7080626 | 0.82 | OXTR (0.72) | OXTRAVPR1AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268418-A1 | PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS | Applied Research Systems ARS Holding N.V. (AN) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001074769-A1 | PHARMACEUTICALLY ACTIVE PYRROLIDINE DERIVATIVES AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-10-11 | — | — | WO | disclosed |