Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OGG1 | O15527 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985832 | 0.83 | NR3C1 (0.46) | MAPTBRD4CREBBPSMN1; SMN2OGG1 | |
| SCHEMBL6980538 | 0.79 | NR3C1 (0.56) | MAPTSMN1; SMN2OGG1NR3C1ALDH1A1 | |
| SCHEMBL6987762 | 0.77 | BRD4 (0.48) | MAPTBRD4CREBBPSMN1; SMN2NR3C1 | |
| SCHEMBL6977885 | 0.71 | NR3C1 (0.48) | BRD4CREBBPSMN1; SMN2NR3C1TSHR | |
| SCHEMBL6984100 | 0.71 | TP53 (0.41) | MAPTSMN1; SMN2ALDH1A1HPGDTP53 | |
| SCHEMBL6982160 | 0.70 | NR3C1 (0.61) | MAPTSMN1; SMN2NR3C1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6984176 | 0.69 | NR3C1 (0.55) | MAPTSMN1; SMN2OGG1NR3C1ALDH1A1 | |
| SCHEMBL6981976 | 0.69 | NR3C1 (0.44) | BRD4CREBBPSMN1; SMN2NR3C1 | |
| SCHEMBL6985835 | 0.69 | SLC16A3 (0.42) | MAPTSMN1; SMN2ALDH1A1TP53LMNA | |
| Iodide SCHEMBL7960088 | 0.69 | ALDH1A1 (0.41) | MAPTBRD4CREBBPSMN1; SMN2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |