Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 6/20 | 0.43 |
| ▸ | TTBK2 | Q6IQ55 | 6/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3534019 | 0.92 | TTBK1 (0.49) | TTBK1TTBK2HDAC6 | |
| SCHEMBL1819928 | 0.80 | TTBK1 (0.52) | TTBK1TTBK2HDAC6 | |
| SCHEMBL18117027 | 0.78 | TTBK1 (0.46) | TTBK1TTBK2HDAC6 | |
| SCHEMBL7090338 | 0.72 | CSF1R (0.47) | — | |
| SCHEMBL16266363 | 0.72 | TTBK1 (0.61) | TTBK1TTBK2HDAC6TNNI3K | |
| SCHEMBL7589835 | 0.72 | TTBK1 (0.57) | TTBK1TTBK2 | |
| SCHEMBL23409028 | 0.71 | TTBK1 (0.59) | TTBK1TTBK2HDAC6TNNI3K | |
| SCHEMBL25069022 | 0.70 | TTBK1 (0.56) | TTBK1TTBK2HDAC6 | |
| SCHEMBL3533626 | 0.70 | JAK3 (0.58) | TTBK1TTBK2 | |
| Hydrochloric Acid SCHEMBL29729076 | 0.70 | TTBK1 (0.58) | TTBK1TTBK2HDAC6TNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212273-A1 | Pyrrolo [2,3-D] pyrimidine compounds | PFIZER INC. | 2003-11-13 | — | — | US | disclosed |
| EP-1087970-A1 | PYRROLO 2,3-d]PYRIMIDINE COMPOUNDS | Pfizer Products Inc. (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065908-A1 | PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS | PFIZER PRODUCTS INC. (US) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212273-A1 | Pyrrolo [2,3-D] pyrimidine compounds | JAK1, JAK3, JAK2 | TTBK1 126/4885TTBK2 242/4885HDAC6 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.