Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTBK1 | Q5TCY1 | 7/20 | 0.57 |
| ▸ | TTBK2 | Q6IQ55 | 7/20 | 0.57 |
| ▸ | AKT2 | P31751 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3534019 | 0.78 | TTBK1 (0.49) | TTBK1TTBK2 | |
| SCHEMBL7087720 | 0.76 | TTBK1 (0.55) | TTBK1TTBK2 | |
| SCHEMBL1819928 | 0.76 | TTBK1 (0.52) | TTBK1TTBK2 | |
| SCHEMBL18117027 | 0.74 | TTBK1 (0.46) | TTBK1TTBK2 | |
| SCHEMBL1899427 | 0.73 | TTBK1 (1.00) | TTBK1TTBK2 | |
| SCHEMBL7855765 | 0.72 | TTBK1 (0.47) | TTBK1TTBK2AKT2GSK3BAKT1 | |
| SCHEMBL7090337 | 0.72 | TTBK1 (0.43) | TTBK1TTBK2 | |
| SCHEMBL7589837 | 0.72 | TTBK1 (0.48) | TTBK1TTBK2AKT2GSK3BAKT1 | |
| SCHEMBL7855767 | 0.71 | JAK3 (0.41) | TTBK1TTBK2AKT2GSK3BAKT1 | |
| SCHEMBL16266363 | 0.71 | TTBK1 (0.61) | TTBK1TTBK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020019526-A1 | Pyrrolo[2,3-d]pyrimidine compounds | PFIZER INC. | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019526-A1 | Pyrrolo[2,3-d]pyrimidine compounds | JAK1, JAK3, JAK2 | TTBK1 126/4885TTBK2 242/4885AKT2 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.