Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048162 | 0.75 | PTGDR2 (0.43) | KMT2AL3MBTL1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL29048193 | 0.69 | PTGDR2 (0.42) | KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL3188853 | 0.69 | KMT2A (0.64) | KMT2AMEN1RIPK1L3MBTL1TSHR | |
| SCHEMBL1948718 | 0.68 | KMT2A (0.52) | KMT2AMEN1RIPK1L3MBTL1CYP2D6 | |
| SCHEMBL27699066 | 0.68 | KMT2A (0.62) | KMT2AMEN1RIPK1L3MBTL1TSHR | |
| SCHEMBL28702537 | 0.68 | RXFP1 (0.34) | KMT2AALDH1A1HRH3 | |
| SCHEMBL9726979 | 0.67 | KMT2A (1.00) | KMT2AMEN1RIPK1L3MBTL1TSHR | |
| SCHEMBL29048188 | 0.67 | MT-CO2 (0.39) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19641147 | 0.66 | CYP2D6 (0.55) | TSHRCYP2D6ALDH1A1POLBCYP2C9 | |
| SCHEMBL835093 | 0.66 | KMT2A (0.64) | KMT2AMEN1RIPK1L3MBTL1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294716-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | Bristol-Myers Squibb Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096331-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |