Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048193 | 0.88 | PTGDR2 (0.42) | PTGDR2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL29048188 | 0.80 | MT-CO2 (0.39) | ELANEALDH1A1KMT2ACYP2C19CYP2C9 | |
| SCHEMBL29048174 | 0.78 | ATM (0.38) | KMT2A | |
| SCHEMBL29048178 | 0.78 | ALDH1A1 (0.33) | PTGDR2ALDH1A1KMT2ACYP2C19CYP3A4 | |
| SCHEMBL29048165 | 0.78 | HTR1A (0.44) | NPSR1ALDH1A1KMT2ACYP2C19CYP3A4 | |
| SCHEMBL29048180 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KMT2ACYP2C19CYP3A4L3MBTL1 | |
| SCHEMBL29048171 | 0.77 | KCNN4 (0.41) | KMT2ASMN1; SMN2 | |
| SCHEMBL7090429 | 0.75 | KMT2A (0.49) | ALDH1A1KMT2ACYP2C19CYP3A4L3MBTL1 | |
| SCHEMBL29048157 | 0.75 | PPARD (0.39) | CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL29048167 | 0.74 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283990-B | Application of substituted pyrrolidone compound as tumor necrosis factor inhibitor | 沈阳药科大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-116283990-A | Application of substituted pyrrolidone compound as tumor necrosis factor inhibitor | 沈阳药科大学 | 2023-06-23 | — | — | CN | disclosed |