Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3255645 | 0.69 | — | — | |
| SCHEMBL13805603 | 0.68 | TSHR (0.44) | TSHRNPSR1 | |
| Ethylene SCHEMBL4351883 | 0.65 | TSHR (0.38) | TSHRNPSR1 | |
| SCHEMBL4637001 | 0.65 | — | — | |
| SCHEMBL10456597 | 0.65 | — | — | |
| Bicarbonate SCHEMBL9560500 | 0.63 | TSHR (0.37) | TSHRNPSR1 | |
| Oxalic Acid SCHEMBL9221357 | 0.62 | TSHR (0.35) | TSHRNPSR1 | |
| SCHEMBL16195686 | 0.60 | TSHR (0.34) | TSHRNPSR1 | |
| SCHEMBL1828884 | 0.60 | TSHR (0.54) | TSHRNPSR1 | |
| SCHEMBL5143482 | 0.59 | TSHR (0.33) | TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240139352-A1 | HER2 BINDERS | GE Precision Healthcare LLC | 2024-05-02 | — | — | US | disclosed |
| US-11633507-B2 | HER2 binders | GENERAL ELECTRIC COMPANY (US) | 2023-04-25 | — | — | US | disclosed |
| EP-3957332-A1 | RADIOLABELED HER2-BINDING PEPTIDE CONJUGATES | General Electric Company (US) | 2022-02-23 | — | — | EP | disclosed |
| EP-3936155-A1 | RADIOLABELED HER2-BINDING PEPTIDE CONJUGATES | General Electric Company (US) | 2022-01-12 | — | — | EP | disclosed |
| EP-2654803-B1 | RADIOLABELED HER2-BINDING PEPTIDE CONJUGATES | GEN ELECTRIC (US) | 2021-08-18 | — | — | EP | disclosed |
| US-20210170057-A1 | HER2 BINDERS | GEN ELECTRIC (US) | 2021-06-10 | — | — | US | disclosed |
| US-10894097-B2 | HER2 binders | GENERAL ELECTRIC COMPANY (US) | 2021-01-19 | — | — | US | disclosed |
| US-20190262481-A1 | HER2 BINDERS | AFFIBODY AB (SE) | 2019-08-29 | — | — | US | disclosed |
| US-10159760-B2 | HER2 binders | GENERAL ELECTRIC COMPANY (US) | 2018-12-25 | — | — | US | disclosed |
| US-20160199521-A1 | HER2 BINDERS | AFFIBODY AB (SE) | 2016-07-14 | — | — | US | disclosed |
| US-20130295010-A1 | HER2 BINDING PEPTIDES LABELLED WITH A 18F - CONTAINING ORGANOSILICON COMPOUND | GE HEALTHCARE LIMITED (GB) | 2013-11-07 | — | — | US | disclosed |
| US-20130287685-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18] FLUORIDE COMPLEXED BY NOTA | GE HEALTHCARE LIMITED (GB) | 2013-10-31 | — | — | US | disclosed |
| EP-2654804-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18]FLUORIDE COMPLEXED BY NOTA | GE Healthcare UK Limited (GB) | 2013-10-30 | — | — | EP | disclosed |
| EP-2654803-A1 | RADIOLABLED HER2 BINDING PEPTIDES | General Electric Company (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012096760-A1 | RADIOLABLED HER2 BINDING PEPTIDES | GENERAL ELECTRIC COMPANY (US) | 2012-07-19 | — | — | WO | disclosed |
| US-20120165650-A1 | HER2 BINDERS | GENERAL ELECTRIC COMPANY (US) | 2012-06-28 | — | — | US | disclosed |
| WO-2012087908-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18] FLUORIDE COMPLEXED BY NOTA | GE HEALTHCARE LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087912-A1 | HER2 BINDING PEPTIDES LABELLED WITH A 18F - CONTAINING ORGANOSILICON COMPOUND | GE HEALTHCARE LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |
| US-8124725-B2 | PDGF-Rβ binders | GENERAL ELECTRIC COMPANY (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090191124-A1 | PDGF-RBeta BINDERS | GENERAL ELECTRIC COMPANY (US) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10894097-B2 | HER2 binders | ERBB2, EGFR, ERBB3 | TSHR 33/4885NPSR1 417/4885 |
| US-20240139352-A1 | HER2 BINDERS | ERBB2, EGFR, ERBB3 | TSHR 64/4885NPSR1 390/4885 |
| US-20130287685-A1 | HER2 BINDING PEPTIDES LABELED WITH ALUMINIUM-[18] FLUORIDE COMPLEXED BY NOTA | ERBB2, EGFR, ERBB3 | TSHR 102/4885NPSR1 507/4885 |
| US-10159760-B2 | HER2 binders | ERBB2, EGFR, ERBB3 | TSHR 64/4885NPSR1 390/4885 |
| US-20210170057-A1 | HER2 BINDERS | ERBB2, EGFR, ERBB3 | TSHR 64/4885NPSR1 390/4885 |
| US-11633507-B2 | HER2 binders | ERBB2, EGFR, ERBB3 | TSHR 64/4885NPSR1 390/4885 |
| US-20130295010-A1 | HER2 BINDING PEPTIDES LABELLED WITH A 18F - CONTAINING ORGANOSILICON COMPOUND | ERBB2, EGFR, ERBB3 | TSHR 137/4885NPSR1 192/4885 |
| US-20090191124-A1 | PDGF-RBeta BINDERS | PDGFRB, PDGFA, PDGFRA | TSHR 571/4885NPSR1 375/4885 |
| US-20160199521-A1 | HER2 BINDERS | ERBB2, EGFR, ERBB3 | TSHR 64/4885NPSR1 390/4885 |
| US-20190262481-A1 | HER2 BINDERS | ERBB2, EGFR, ERBB3 | TSHR 33/4885NPSR1 417/4885 |
| US-20120165650-A1 | HER2 BINDERS | ERBB2, EGFR, ERBB3 | TSHR 33/4885NPSR1 417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.