Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ADH1B | P00325 | 2/20 | 0.37 |
| ▸ | ADH1C | P00326 | 2/20 | 0.37 |
| ▸ | ADH1A | P07327 | 2/20 | 0.37 |
| ▸ | ADH7 | P40394 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | ADH4 | P08319 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698951 | 0.87 | TSHR (0.41) | TSHRALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL3694091 | 0.84 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL13483931 | 0.81 | TSHR (0.40) | TSHRALDH1A1FAAHTRPV1 | |
| SCHEMBL10898045 | 0.81 | TSHR (0.40) | TSHRALDH1A1FAAHTRPV1 | |
| SCHEMBL10898051 | 0.81 | TSHR (0.40) | TSHRALDH1A1FAAHTRPV1 | |
| SCHEMBL16886977 | 0.81 | FAAH (0.46) | TSHRALDH1A1FAAHTRPV1PPARA | |
| SCHEMBL24183668 | 0.79 | TSHR (0.44) | TSHRFAAHTRPV1 | |
| SCHEMBL11760319 | 0.79 | TSHR (0.44) | TSHRFAAHTRPV1 | |
| SCHEMBL11760325 | 0.79 | TSHR (0.44) | TSHRFAAHTRPV1 | |
| SCHEMBL21581093 | 0.79 | TSHR (0.44) | TSHRFAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6573357-B1 | Contacting a ketone with a polyamine; removing a water by-product produced in the reaction mixture; removing the excess of ketone reactant from the reaction mixture and recycling a portion of it; recovering ketimine | RESOLUTION PERFORMANCE PRODUCTS LLC | 2003-06-03 | — | — | US | disclosed |