Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | HTR7 | P34969 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491645 | 1.00 | DRD2 (0.49) | DRD2SLC6A4HTR1DADRA1DHTR2A | |
| SCHEMBL29116463 | 0.86 | KDM4E (0.54) | DRD2ADRA1DHTR2AHTR7KCNH2 | |
| SCHEMBL6493987 | 0.86 | DRD2 (0.55) | DRD2SLC6A4HTR1DADRA1DHTR2A | |
| SCHEMBL4882143 | 0.85 | DRD2 (0.56) | DRD2SLC6A4ADRA1DHTR2AHTR7 | |
| SCHEMBL6499703 | 0.82 | GPR119 (0.35) | SLC6A4HTR1D | |
| SCHEMBL6502071 | 0.82 | JAK2 (0.35) | SLC6A4HTR1D | |
| SCHEMBL31530781 | 0.80 | SLC6A4 (0.47) | DRD2SLC6A4HTR1DADRA1DHTR2A | |
| SCHEMBL22871576 | 0.80 | SLC6A4 (0.47) | DRD2SLC6A4HTR1DADRA1DHTR2A | |
| SCHEMBL12329382 | 0.78 | DRD2 (0.40) | DRD2SLC6A4HTR1DADRA1DHTR2A | |
| SCHEMBL12329638 | 0.78 | HTR2A (0.42) | DRD2SLC6A4ADRA1DHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286992-A1 | PIPERIDYINDOLES AS SEROTONIN RECEPTOR LIGANDS | ELI LILLY AND COMPANY (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087881-A1 | PIPERIDYINDOLES AS SEROTONIN RECEPTOR LIGANDS | ELI LILLY AND COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |