Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987743 | 0.88 | HPGD (0.53) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL6990917 | 0.84 | NPC1 (0.41) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL6987742 | 0.75 | HPGD (0.38) | ALDH1A1KMT2AMEN1GAAFAAH | |
| SCHEMBL6988288 | 0.75 | CCNC (0.39) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL6990002 | 0.72 | NPC1 (0.53) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL6995342 | 0.72 | CDC7 (0.50) | HTTKMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL9371939 | 0.68 | ALDH1A1 (1.00) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL6989475 | 0.67 | TRPM8 (0.41) | ALDH1A1HTTKMT2AMEN1GAA | |
| SCHEMBL6986492 | 0.65 | MEN1 (0.36) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL6989907 | 0.65 | CCNC (0.52) | ALDH1A1HTTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931074-B1 | CONDENSED 4,5,6,7-TETRAHYDROBENZO C]THIOPHENES AS ENHANCER FOR CELL DIFFERENTIATION INDUCTION FACTOR ACTION | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-07 | — | — | EP | claimed |