Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | MPC2 | O95563 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526188 | 0.89 | FFAR1 (0.59) | FFAR1PPARGMCHR1MPC2CYP2C8 | |
| SCHEMBL6185086 | 0.86 | FFAR1 (0.55) | FFAR1PPARGMCHR1MPC2CYP2C8 | |
| SCHEMBL7565841 | 0.84 | FFAR1 (0.52) | FFAR1PPARGMCHR1MPC2CYP2C8 | |
| SCHEMBL7089664 | 0.84 | FFAR1 (0.52) | FFAR1PPARGMCHR1MPC2CYP2C8 | |
| SCHEMBL6477698 | 0.84 | FFAR1 (0.57) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6473379 | 0.83 | FFAR1 (0.61) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5399583 | 0.83 | FFAR1 (0.61) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6181638 | 0.83 | FFAR1 (0.52) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6477731 | 0.80 | FFAR1 (0.51) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6473029 | 0.79 | FFAR1 (0.55) | FFAR1PPARGMPC2CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | claimed |
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | claimed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | claimed |
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | disclosed |