Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.55 |
| ▸ | PPARG | P37231 | 7/20 | 0.49 |
| ▸ | MPC2 | O95563 | 2/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473379 | 0.94 | FFAR1 (0.61) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6477731 | 0.92 | FFAR1 (0.51) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6477698 | 0.85 | FFAR1 (0.57) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6526188 | 0.84 | FFAR1 (0.59) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6185086 | 0.83 | FFAR1 (0.55) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6473032 | 0.82 | FFAR1 (0.55) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL5399583 | 0.80 | FFAR1 (0.61) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL7565841 | 0.80 | FFAR1 (0.52) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL7089664 | 0.80 | FFAR1 (0.52) | FFAR1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL7090957 | 0.79 | FFAR1 (0.49) | FFAR1PPARGMPC2CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908939-B2 | Biaromatic ligand activators of PPARγ receptors | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2005-06-21 | — | — | US | claimed |