Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MPC2 | O95563 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6526188 | 0.89 | FFAR1 (0.59) | FFAR1MCHR1PPARGPPARAMAPT | |
| SCHEMBL7089664 | 0.87 | FFAR1 (0.52) | FFAR1MCHR1PPARGPPARAALDH1A1 | |
| SCHEMBL5399583 | 0.85 | FFAR1 (0.61) | FFAR1PPARGPPARAALDH1A1NPSR1 | |
| SCHEMBL7090957 | 0.84 | FFAR1 (0.49) | FFAR1MCHR1PPARGPPARAMAPT | |
| SCHEMBL6185086 | 0.83 | FFAR1 (0.55) | FFAR1MCHR1PPARGPPARAMPC2 | |
| SCHEMBL6473379 | 0.82 | FFAR1 (0.61) | FFAR1PPARGPPARAMAPTMPC2 | |
| SCHEMBL6477698 | 0.81 | FFAR1 (0.57) | FFAR1PPARGPPARAMAPTMPC2 | |
| SCHEMBL6473789 | 0.81 | FFAR1 (0.58) | FFAR1PPARGPPARAALDH1A1MAPT | |
| SCHEMBL6473029 | 0.80 | FFAR1 (0.55) | FFAR1PPARGPPARAMPC2CYP2C8 | |
| SCHEMBL6184625 | 0.79 | FFAR1 (0.61) | FFAR1PPARGMAPTMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | claimed |