Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28734247 | 0.98 | HTR6 (0.51) | HTR6HTR2AMAOACYP3A4TAAR1 | |
| SCHEMBL27460809 | 0.90 | HTR2A (0.40) | HTR6HTR2ACYP3A4HSD17B10MEN1 | |
| SCHEMBL1028466 | 0.84 | HTR2A (0.39) | HTR6HTR2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL2830664 | 0.82 | PRCP (0.39) | HTR6HTR2ACYP3A4HSD17B10TDP1 | |
| SCHEMBL9145143 | 0.82 | HTR2A (0.38) | HTR6HTR2ACYP3A4HSD17B10KDM4E | |
| Ammonia Solution, Strong SCHEMBL21245914 | 0.82 | HTR2A (0.38) | HTR6HTR2ACYP3A4HSD17B10KDM4E | |
| Lithium SCHEMBL9145147 | 0.82 | HTR2A (0.38) | HTR6HTR2ACYP3A4HSD17B10KDM4E | |
| Methane SCHEMBL28813011 | 0.82 | HTR2A (0.38) | HTR6HTR2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL9145856 | 0.82 | HTR2A (0.38) | HTR6HTR2ACYP3A4HSD17B10KDM4E | |
| SCHEMBL9145850 | 0.82 | HTR2A (0.38) | HTR6HTR2ACYP3A4HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910560-B1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6271411-B1 | REACTING AN INDENE WITH AN ARENE COMPOUND SUBSTITUTED WITH AN HALOGEN ATOM, PREFERABLY A IODINE ATOM, OR WITH AN ORGANOSULPHONATE GROUP, IN A BASIC MEDIUM IN THE PRESENCE OF A PALLADIUM CATALYST. | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-08-07 | — | — | US | disclosed |
| CN-1228072-A | Process for preparing 2-aryl-substituted indenes | MONTELL TECHNOLOGY COMPANY BV (NL) | 1999-09-08 | — | — | CN | disclosed |
| EP-0910560-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | Montell Technology Company bv (NL) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998046547-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-10-22 | — | — | WO | disclosed |