Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699904 | 0.88 | HPGD (0.54) | HPGDHSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL28644871 | 0.86 | HPGD (0.53) | HPGDHSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL4819311 | 0.86 | HPGD (0.43) | HPGDHSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL1788131 | 0.85 | HPGD (0.51) | HPGDHSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL28628766 | 0.84 | MAPT (0.46) | HPGDHSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL18489613 | 0.83 | HPGD (0.51) | HPGDHSD17B10KDM4EXBP1ALDH1A1 | |
| SCHEMBL29437924 | 0.82 | HSD17B10 (0.76) | HPGDHSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL69868 | 0.82 | HSD17B10 (0.76) | HPGDHSD17B10ALOX15MAPTKDM4E | |
| Hydrogen Peroxide SCHEMBL28473316 | 0.81 | TSHR (0.57) | HPGDHSD17B10ALOX15MAPTKDM4E | |
| SCHEMBL739463 | 0.80 | TSHR (0.47) | HPGDXBP1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103351402-A | Method for production of phosphate flame retardant by excess phosphorus oxychloride | Tianjin lianrui flame retardant material co ltd | 2013-10-16 | — | — | CN | disclosed |
| CN-103224525-A | Method for producing IPPP 65 | Tianjin lianrui flame retardant material co ltd | 2013-07-31 | — | — | CN | disclosed |
| CN-103224524-A | Method for producing IPPP 95 | Tianjin lianrui flame retardant material co ltd | 2013-07-31 | — | — | CN | disclosed |
| CN-103224526-A | Method for producing IPPP 35 | Tianjin lianrui flame retardant material co ltd | 2013-07-31 | — | — | CN | disclosed |
| CN-103214518-A | Method for producing IPPP (Isopropyl Phenyl diphenyl Phosphate) | Tianjin lianrui flame retardant material co ltd | 2013-07-24 | — | — | CN | disclosed |
| CN-103214516-A | Method for producing IPPP (Isopropyl Phenyl diphenyl Phosphate) 50 | Tianjin lianrui flame retardant material co ltd | 2013-07-24 | — | — | CN | disclosed |
| CN-1215123-C | Polyamide and polyolefine refractory composition | ATOFINA (FR) | 2005-08-17 | — | — | CN | disclosed |
| CN-1468906-A | Polyamide and polyolefine refractory composition | ���з��ɹ�˾ | 2004-01-21 | — | — | CN | disclosed |
| US-20030171422-A1 | New nitromethyl ketones, process for preparing them and compositions containing them | MERCK PATENT GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6559185-B2 | Nitromethyl ketone compounds having aldose reduction inhibiting properties and methods for their use | MERCK PATENT GMBH (DE) | 2003-05-06 | — | — | US | disclosed |
| US-20030069312-A1 | Antidiabetic agents | LARDY CLAUDE (FR) | 2003-04-10 | — | — | US | disclosed |
| US-6043281-A | ALDOSE REDUCTASE INHIBITORS; TREATMENT OR PREVENTION OF COMPLICATIONS OF DIABETES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0983226-A1 | NEW NITROMETHYL KETONES, PROCESS FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | MERCK PATENT GmbH (DE) | 2000-03-08 | — | — | EP | disclosed |
| US-5932765-A | REDUCTASE INHIBITORS | MERCK PATENT GESELLSCHAFT MIT (DE) | 1999-08-03 | — | — | US | disclosed |
| WO-1998052906-A1 | NEW NITROMETHYL KETONES, PROCESS FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | MERCK PATENT GMBH (DE) | 1998-11-26 | — | — | WO | disclosed |
| EP-0125641-B1 | ALKANOYLOXYBENZENESULFONATE SALT PRODUCTION | ETHYL CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |
| US-4537724-A | Alkanoyloxybenzenesulfonate salt production | ETHYL CORPORATION (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0125641-A2 | Alkanoyloxybenzenesulfonate salt production | ETHYL CORPORATION (US) | 1984-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069312-A1 | Antidiabetic agents | SLC5A1, SLC5A2, GPR119 | HPGD 964/4885HSD17B10 294/4885ALOX15 1007/4885 |
| US-20030171422-A1 | New nitromethyl ketones, process for preparing them and compositions containing them | AKR1B1, AKR1A1, AKR1C1 | HPGD 231/4885HSD17B10 183/4885ALOX15 1166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.