Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.48 |
| ▸ | CA1 | P00915 | 8/20 | 0.46 |
| ▸ | CA9 | Q16790 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091721 | 1.00 | CA2 (0.48) | CA2CA1CA9CA12CYP2C19 | |
| SCHEMBL7089757 | 0.85 | CA2 (0.44) | CA2CA1CA9CA12LMNA | |
| SCHEMBL7089756 | 0.85 | CA2 (0.44) | CA2CA1CA9CA12LMNA | |
| SCHEMBL7092581 | 0.83 | CA2 (0.59) | CA2CA1CA9CA12LMNA | |
| SCHEMBL7092580 | 0.83 | CA2 (0.59) | CA2CA1CA9CA12LMNA | |
| SCHEMBL28160464 | 0.79 | CA2 (0.45) | CA2CA1CA9CA12LMNA | |
| SCHEMBL28790109 | 0.79 | CA2 (0.45) | CA2CA1CA9CA12LMNA | |
| SCHEMBL27493474 | 0.77 | CA2 (0.43) | CA2CA1CA9CA12LMNA | |
| SCHEMBL7786989 | 0.72 | CA2 (0.44) | CA2CA1CA9CA12LMNA | |
| SCHEMBL7786991 | 0.72 | CA2 (0.44) | CA2CA1CA9CA12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087127-A2 | ANTIMICROBIAL COMPOUNDS AGAINST STAPHYLOCOCCI, MYCOBACTERIA, AND OTHER INFECTIOUS AGENTS | EXEGENICS INC. (US) | 2003-10-23 | — | — | WO | disclosed |