Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.59 |
| ▸ | CA1 | P00915 | 7/20 | 0.59 |
| ▸ | CA9 | Q16790 | 6/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.59 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | CTBP2 | P56545 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092581 | 1.00 | CA2 (0.59) | CA2CA1CA9CA12FNTA | |
| SCHEMBL7089757 | 0.83 | CA2 (0.44) | CA2CA1CA9CA12CTBP2 | |
| SCHEMBL7091722 | 0.83 | CA2 (0.48) | CA2CA1CA9CA12LMNA | |
| SCHEMBL7091721 | 0.83 | CA2 (0.48) | CA2CA1CA9CA12LMNA | |
| SCHEMBL7089756 | 0.83 | CA2 (0.44) | CA2CA1CA9CA12CTBP2 | |
| SCHEMBL28160464 | 0.81 | CA2 (0.45) | CA2CA1CA9CA12LMNA | |
| SCHEMBL28790109 | 0.81 | CA2 (0.45) | CA2CA1CA9CA12LMNA | |
| SCHEMBL27493474 | 0.79 | CA2 (0.43) | CA2CA1CA9CA12LMNA | |
| SCHEMBL11110698 | 0.79 | CTBP2 (0.59) | CA2CA1CA9CA12FNTA | |
| SCHEMBL11110696 | 0.79 | CTBP2 (0.59) | CA2CA1CA9CA12FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087127-A2 | ANTIMICROBIAL COMPOUNDS AGAINST STAPHYLOCOCCI, MYCOBACTERIA, AND OTHER INFECTIOUS AGENTS | EXEGENICS INC. (US) | 2003-10-23 | — | — | WO | disclosed |