Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708675 | 0.89 | MAPT (0.52) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6710973 | 0.88 | MAPT (0.52) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL7092378 | 0.83 | MAPT (0.43) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6763043 | 0.77 | MAPT (0.53) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6708674 | 0.73 | MAPT (0.52) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6710876 | 0.72 | MAPT (0.53) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6708390 | 0.72 | MAPT (0.52) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6709628 | 0.71 | MAPT (0.55) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6759314 | 0.69 | ALDH1A1 (0.41) | MAPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL6760873 | 0.68 | HRH4 (0.48) | ALDH1A1LMNAHTR2BHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324999-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2003-07-09 | — | — | EP | claimed |
| WO-2002030927-A1 | NOVEL AMINOPHENYL PIPERAZINE OR AMINOPHENYL PIPERIDINE DERIVATIVES INHIBITING PRENYL TRANSFERASE PROTEINS AND METHODS FOR PREPARING SAME | PIERRE FABRE MEDICAMENT (FR) | 2002-04-18 | — | — | WO | claimed |