Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526840 | 0.78 | FOS (0.47) | MAOBMAPTLMNA | |
| SCHEMBL19968585 | 0.77 | ALDH1A1 (0.40) | MAOB | |
| SCHEMBL29350410 | 0.77 | ALDH1A1 (0.40) | MAOB | |
| SCHEMBL16242193 | 0.74 | TUBB1 (0.41) | MAOBMAPTHDAC6LMNAHTT | |
| SCHEMBL24786796 | 0.73 | MAOB (0.33) | MAOB | |
| SCHEMBL23457991 | 0.72 | MAOB (0.61) | MAOBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23457993 | 0.72 | MAOB (0.61) | MAOBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27486273 | 0.71 | MAOB (0.58) | MAOBMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL5245151 | 0.71 | MAOB (0.58) | MAOBMAPTHDAC3HDAC4HDAC1 | |
| SCHEMBL3692947 | 0.67 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924251-B1 | Ductile, gamma radiation resistant polyolefin composition and articles produced therefrom | BASELL NORTH AMERICA INC (US) | 2003-08-13 | — | — | EP | claimed |
| EP-0814127-B1 | Embrittlement-resistant polyolefin composition and flexible articles therefrom | MONTELL NORTH AMERICA INC (US) | 2001-08-16 | — | — | EP | claimed |
| EP-0814128-B1 | Embrittlement-resistant polyolefin composition and flexible articles therefrom | MONTELL NORTH AMERICA INC (US) | 1999-12-08 | — | — | EP | claimed |
| EP-0651006-B1 | Piperidinyl phosphite compositions and polyolefin compositions containing them | MONTELL NORTH AMERICA INC (US) | 1998-03-11 | — | — | EP | claimed |