SCHEMBL709242

SCHEMBL709242

CNS(=O)(=O)c1ccc(F)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.64
GAA P10253 1/20 0.64
CA1 P00915 4/20 0.61
CA2 P00918 4/20 0.61
CA12 O43570 2/20 0.61
CA3 P07451 2/20 0.61
CA4 P22748 2/20 0.61
CA6 P23280 2/20 0.61
CA5A P35218 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA13 Q8N1Q1 2/20 0.61
CA14 Q9ULX7 2/20 0.61
CA5B Q9Y2D0 2/20 0.61
MMP1 P03956 1/20 0.61
MMP2 P08253 1/20 0.61
MMP9 P14780 1/20 0.61
MMP8 P22894 1/20 0.61
MMP13 P45452 1/20 0.61
PTGS2 P35354 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27924843 0.98 SMN1; SMN2 (0.61) SMN1; SMN2GAACA1CA2CA12
SCHEMBL28750635 0.88 SMN1; SMN2 (0.81) SMN1; SMN2GAACA1CA2CA12
SCHEMBL7629070 0.87 SMN1; SMN2 (0.80) SMN1; SMN2GAACA1CA2CA12
Acrylic Acid SCHEMBL30115050 0.84 CA1 (0.50) SMN1; SMN2GAACA1CA2CA12
SCHEMBL5071852 0.82 PTGS2 (0.69) SMN1; SMN2GAAPTGS2KIF11
SCHEMBL8080277 0.80 SMN1; SMN2 (0.70) SMN1; SMN2GAACA1CA2CA12
SCHEMBL12945093 0.80 CA1 (0.67) CA1CA2MMP1MMP2MMP9
SCHEMBL3818860 0.78 CA1 (0.64) CA1CA2MMP1MMP2MMP9
SCHEMBL30960 0.78 GAA (1.00) SMN1; SMN2GAACA1CA2CA12
SCHEMBL18932693 0.78 CA1 (0.64) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP claimed
EP-2057115-B9 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES ARRAY BIOPHARMA INC (US) 2012-12-26 EP claimed
EP-2057115-B1 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES ARRAY BIOPHARMA INC (US) 2012-10-03 EP claimed
US-8183289-B2 4-substituted phenoxyphenylacetic acid derivatives ARRAY BIOPHARMA INC. (US) 2012-05-22 US claimed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US claimed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO claimed
US-20100173955-A1 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES ARRAY BIOPHARMA INC. (US) 2010-07-08 US claimed
EP-2057115-A1 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES Array Biopharma, Inc. (US) 2009-05-13 EP claimed
WO-2008024746-A1 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES ARRAY BIOPHARMA, INC. (US) 2008-02-28 WO claimed
CN-120117949-A Method for directly preparing tertiary amine compound from aromatic aldehyde, ketone and secondary amine 湖南大学 2025-06-10 CN disclosed
EP-4399216-A1 IMMUNOMODULATING AZALIDES Zoetis Services LLC (US) 2024-07-17 EP disclosed
US-20230348441-A1 BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR MEDSHINE DISCOVERY INC. (CN) 2023-11-02 US disclosed
WO-2023038852-A1 IMMUNOMODULATING AZALIDES ZOETIS SERVICES LLC (US) 2023-03-16 WO disclosed
CN-115551864-A Substituted tricyclic amides, analogs thereof, and methods of using the same 爱彼特生物制药公司 2022-12-30 CN disclosed
US-4971620-A APPLYING TO FIELDS TO KILL WEEDS MITSUBISHI KASEI CORPORATION (JP) 1990-11-20 US disclosed
CN-1036564-A Sulfanilamide (SN) and contain the weedkiller of sulfanilamide (SN) as activeconstituents MITSUBISHI CHEM IND (JP) 1989-10-25 CN disclosed
EP-0326170-A1 Sulfonamide and herbicide containing the same as active ingredient MITSUBISHI KASEI CORPORATION (JP) 1989-08-02 EP disclosed
US-4788196-A Phenyl piperazine anti-arrhythmia agents PFIZER INC. (US) 1988-11-29 US disclosed
EP-0244115-A2 Phenyl-piperazine anti-arrhythmia agents Pfizer Limited (GB) 1987-11-04 EP disclosed
CN-87102873-A Phenylpiperazine anti-dysrhythmia agents and preparation method thereof 1987-10-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348441-A1 BICYCLIC COMPOUND THAT ACTS AS CRBN PROTEIN REGULATOR CRBN, CRKL, NCOR1 SMN1; SMN2 2827/4885GAA 4139/4885CA1 3580/4885
US-20100173955-A1 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES CD22, HRH2, CD74 SMN1; SMN2 3361/4885GAA 2523/4885CA1 1950/4885
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS STS, ARSA, TST SMN1; SMN2 4603/4885GAA 218/4885CA1 4599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.