Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 0.69 |
| ▸ | MMP12 | P39900 | 18/20 | 0.69 |
| ▸ | MMP9 | P14780 | 17/20 | 0.69 |
| ▸ | MMP2 | P08253 | 17/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959481 | 0.82 | MMP1 (1.00) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL1255803 | 0.79 | MMP1 (0.69) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL1837744 | 0.78 | MMP1 (0.58) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL30636847 | 0.78 | MMP1 (0.76) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL1839298 | 0.78 | MMP1 (0.44) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL12279181 | 0.78 | MMP1 (0.44) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL22959440 | 0.78 | MMP1 (0.76) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL22959461 | 0.78 | MMP1 (1.00) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL13446064 | 0.78 | MMP2 (0.58) | MMP1MMP12MMP9MMP2 | |
| SCHEMBL1838232 | 0.75 | KMT2A (0.47) | MMP1MMP12MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351959-A1 | NOVEL PLEUROMUTILIN DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002030929-A1 | NOVEL PLEUROMUTILIN DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-04-18 | — | — | WO | disclosed |