Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419395 | 0.84 | MEN1 (0.63) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL21669395 | 0.84 | RAB9A (0.61) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL9725349 | 0.83 | RAB9A (0.64) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL15255347 | 0.82 | RAB9A (0.67) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL763168 | 0.82 | CYP1A2 (0.74) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL29695523 | 0.82 | CYP1A2 (0.74) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL17749581 | 0.82 | MAPT (0.55) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL10728078 | 0.81 | MEN1 (0.58) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL6902600 | 0.80 | RAB9A (0.72) | RAB9AMEN1CYP1A2KMT2ALMNA | |
| SCHEMBL30546561 | 0.79 | LMNA (0.64) | RAB9AMEN1CYP1A2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330451-A2 | SUBSTITUTED BENZIMIDAZOL-2-ONES AS VASOPRESSIN RECEPTOR ANTAGONISTS AND NEUROPEPTIDE Y MODULATORS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002100861-A1 | 1-(3-PHENYLOXYPROPYL)PIPERIDINE DERIVATIVES | AKZO NOBEL N.V. (NL) | 2002-12-19 | — | — | WO | disclosed |
| WO-2002055514-A2 | SUBSTITUTED BENZIMIDAZOL-2-ONES AS VASOPRESSIN RECEPTOR ANTAGONISTS AND NEUROPEPTIDE Y MODULATORS | ORTHO MCNEIL PHARM INC (US) | 2002-07-18 | — | — | WO | disclosed |
| US-5162318-A | Which have pulmonary surfactant secretion promoting activity | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |