Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 10/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744602 | 0.82 | GRIK1 (0.57) | GPR52 | |
| SCHEMBL5744604 | 0.82 | GRIK1 (0.57) | GPR52 | |
| SCHEMBL7241565 | 0.77 | CHRNA7 (0.57) | TBXAS1NAPRTCHRNA7CYP2A6CYP1A2 | |
| SCHEMBL8514458 | 0.75 | GPR52 (0.65) | TBXAS1NAPRTCHRNA7GPR52 | |
| SCHEMBL8514462 | 0.75 | GPR52 (0.65) | TBXAS1NAPRTCHRNA7GPR52 | |
| Oxalic Acid SCHEMBL27256580 | 0.74 | TBXAS1 (0.60) | TBXAS1NAPRTRECQLCHRNA7CYP2A6 | |
| SCHEMBL83186 | 0.74 | RECQL (0.62) | TBXAS1NAPRTRECQLCHRNA7CYP2A6 | |
| SCHEMBL9242333 | 0.74 | TBXAS1 (0.56) | TBXAS1PTAFR | |
| SCHEMBL2019608 | 0.74 | TBXAS1 (0.56) | TBXAS1PTAFR | |
| SCHEMBL348856 | 0.73 | CHRNA7 (0.57) | TBXAS1NAPRTCHRNA7CYP2A6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076440-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS CALCITONIN AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-18 | — | — | WO | disclosed |