Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL890924 | 0.90 | — | — | |
| SCHEMBL28256185 | 0.88 | TSHR (0.34) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL28427720 | 0.88 | TSHR (0.42) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL28172352 | 0.88 | — | — | |
| SCHEMBL28171680 | 0.88 | — | — | |
| Azepane SCHEMBL28329112 | 0.85 | TSHR (0.34) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL11475296 | 0.81 | — | — | |
| SCHEMBL27647169 | 0.79 | TSHR (0.35) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL11488587 | 0.79 | — | — | |
| Bicarbonate SCHEMBL11493509 | 0.77 | CHRM3 (0.37) | TSHRHSD17B10THRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011670-A2 | Cycloheptatriene derivatives and process for their preparation | BAYER AG (DE) | 1980-06-11 | — | — | EP | claimed |
| CN-106459002-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-107699581-A | 3,7 dihydroxy Zhuo phenolic ketone biological synthesis gene clusters and its application | 上海交通大学 | 2018-02-16 | — | — | CN | disclosed |
| US-6660863-B2 | Reacting an cycloheptatriene nitrile compound with nortropane compound | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-12-09 | — | — | US | disclosed |
| US-6596868-B2 | Reacting a cycloheptatriene derivative with a primary amine or ammonia in the presence of a base | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |
| US-20030109708-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS CO., LTD. | 2003-06-12 | — | — | US | disclosed |
| US-20010020096-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2001-09-06 | — | — | US | disclosed |
| EP-1127887-A1 | Process for synthesizing anhydroecgonine derivative | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 2001-08-29 | — | — | EP | disclosed |
| CN-1054601-A | Azabicyclo and azepine cyclic oximes and amine cholinergic agents thing and methods of treatment thereof | WARNER LAMBERT CO (US) | 1991-09-18 | — | — | CN | disclosed |
| EP-0011670-A3 | CYCLOHEPTATRIENE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1980-08-20 | — | — | EP | disclosed |
| EP-0011670-A2 | Cycloheptatriene derivatives and process for their preparation | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
| EP-0011670-A2 | Cycloheptatriene derivatives and process for their preparation | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
| EP-0011669-A1 | Cycloheptatriene compounds and process for the preparation of cycloheptatriene compounds | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109708-A1 | Process for synthesizing anhydroecgonine derivative | CES2, NPR1, OPRL1 | TSHR 3513/4885MAPK1 842/4885HSD17B10 462/4885 |
| US-20010020096-A1 | Process for synthesizing anhydroecgonine derivative | CES2, NPR1, OPRL1 | TSHR 3513/4885MAPK1 842/4885HSD17B10 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.