Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 9/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152253 | 0.82 | POLB (0.63) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6816361 | 0.73 | POLB (0.73) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10813692 | 0.71 | POLB (0.75) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10813685 | 0.71 | POLB (0.75) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL6651050 | 0.71 | MEN1 (0.74) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL23867550 | 0.70 | POLB (0.76) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL19944328 | 0.70 | POLB (0.73) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| Ammonia Solution, Strong SCHEMBL29042444 | 0.70 | MEN1 (0.72) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL13185637 | 0.68 | POLB (0.70) | POLBNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5206520 | 0.68 | MEN1 (0.69) | POLBNPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341755-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GmbH (DE) | 2003-09-10 | — | — | EP | claimed |
| WO-2002048099-A1 | CARBOXYLIC ACID AMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF THROMBOEMBOLIC DISEASES AND TUMOURS | MERCK PATENT GMBH (DE) | 2002-06-20 | — | — | WO | claimed |