Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644358 | 0.94 | POLB (0.46) | POLBLMNAL3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL1644521 | 0.87 | POLB (0.70) | POLBLMNAL3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL27594663 | 0.82 | LMNA (0.44) | POLBLMNAL3MBTL1ALDH1A1RXFP1 | |
| SCHEMBL1019601 | 0.80 | CYP1A2 (0.59) | POLBLMNAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL13635198 | 0.78 | POLB (0.46) | POLBLMNAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL30445565 | 0.78 | POLB (0.46) | POLBLMNAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL2960339 | 0.78 | POLB (0.50) | POLBLMNAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL12184767 | 0.78 | POLB (0.46) | POLBLMNAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL31390501 | 0.78 | MAPK1 (0.47) | POLBLMNAL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL480161 | 0.78 | MAPK1 (0.47) | POLBLMNAL3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076440-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS CALCITONIN AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-18 | — | — | WO | disclosed |