Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1885307 | 0.98 | MAPT (0.75) | MAPTALDH1A1ALOX12L3MBTL1CYP1A2 | |
| Diphenylamine SCHEMBL28104923 | 0.88 | MAPT (0.64) | MAPTALDH1A1ALOX12L3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9152852 | 0.87 | ALDH1A1 (0.95) | MAPTALDH1A1ALOX12L3MBTL1CYP1A2 | |
| Hydrochloric Acid SCHEMBL479764 | 0.87 | ALDH1A1 (0.95) | MAPTALDH1A1ALOX12L3MBTL1CYP1A2 | |
| SCHEMBL6405773 | 0.85 | ALDH1A1 (1.00) | MAPTALDH1A1ALOX12L3MBTL1CYP1A2 | |
| SCHEMBL13644737 | 0.85 | ALDH1A1 (1.00) | MAPTALDH1A1ALOX12L3MBTL1CYP1A2 | |
| SCHEMBL22282997 | 0.85 | ALDH1A1 (1.00) | MAPTALDH1A1ALOX12L3MBTL1CYP1A2 | |
| SCHEMBL28848194 | 0.85 | ALDH1A1 (1.00) | MAPTALDH1A1ALOX12L3MBTL1CYP1A2 | |
| SCHEMBL15371 | 0.85 | ALDH1A1 (1.00) | MAPTALDH1A1ALOX12L3MBTL1CYP1A2 | |
| Diphenylamine SCHEMBL28553827 | 0.85 | MAPT (0.71) | MAPTALDH1A1ALOX12L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030074743-A1 | Hair dye composition | LION CORPORATION (JP) | 2003-04-24 | — | — | US | disclosed |
| EP-1240890-A1 | HAIR DYE COMPOSITION | Lion Corporation (JP) | 2002-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030074743-A1 | Hair dye composition | HAAO, GRHPR, CD44 | MAPT 837/4885ALDH1A1 10/4885ALOX12 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.