Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | TOP1 | P11387 | 3/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093389 | 0.87 | CYP11B1 (0.34) | KIF11TOP1NPY5RPDCD1CD274 | |
| SCHEMBL7090601 | 0.85 | KMT2A (0.44) | KIF11NISCHTRPV1AKT1CYP11B1 | |
| SCHEMBL7094267 | 0.83 | CYP11B1 (0.37) | TOP1NPC1BCHEACHEBACE1 | |
| SCHEMBL7094263 | 0.81 | CYP11B1 (0.45) | NPC1NISCHSLC6A7CYP11B1CYP11B2 | |
| SCHEMBL7095208 | 0.80 | CYP11B1 (0.47) | NPC1CYP11B1CYP11B2 | |
| SCHEMBL7096288 | 0.80 | CYP11B1 (0.37) | NPY5RPDCD1CD274NPC1BCHE | |
| SCHEMBL7093600 | 0.80 | CYP11B1 (0.41) | CD274NPC1NISCHACHEBACE1 | |
| SCHEMBL7090626 | 0.78 | CYP11B1 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL7094835 | 0.76 | CLK4 (0.49) | PDCD1CD274NPC1ACHECYP11B1 | |
| SCHEMBL6285696 | 0.74 | CYP11B1 (0.49) | KIF11NISCHBACE1SCN2ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910560-B1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6271411-B1 | REACTING AN INDENE WITH AN ARENE COMPOUND SUBSTITUTED WITH AN HALOGEN ATOM, PREFERABLY A IODINE ATOM, OR WITH AN ORGANOSULPHONATE GROUP, IN A BASIC MEDIUM IN THE PRESENCE OF A PALLADIUM CATALYST. | MONTELL TECHNOLOGY COMPANY BV (NL) | 2001-08-07 | — | — | US | disclosed |
| EP-0910560-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | Montell Technology Company bv (NL) | 1999-04-28 | — | — | EP | disclosed |
| WO-1998046547-A1 | PROCESS FOR PREPARING 2-ARYL-SUBSTITUTED INDENES | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-10-22 | — | — | WO | disclosed |