Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17766647 | 0.89 | ALDH1A1 (0.54) | BCAT2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL11411919 | 0.84 | ALDH1A1 (0.58) | BCAT2ALDH1A1MAPTKDM4EHPGD | |
| Benzene SCHEMBL27395742 | 0.82 | ALDH1A1 (0.67) | BCAT2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL8477209 | 0.82 | SIRT2 (0.47) | BCAT2ALDH1A1MAPTKDM4EHPGD | |
| Carbamic Acid SCHEMBL28336611 | 0.79 | ALDH1A1 (0.64) | BCAT2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL27700719 | 0.79 | ALDH1A1 (0.70) | BCAT2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL4967588 | 0.79 | ALDH1A1 (0.70) | BCAT2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL39118 | 0.79 | ALDH1A1 (0.70) | BCAT2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL29872360 | 0.78 | KDM4E (0.59) | BCAT2ALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL1520940 | 0.78 | KDM4E (0.59) | BCAT2ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232994-A1 | Bicyclic thiophene derivatives and combinatorial libraries thereof | LION BIOSCIENCE AG (DE) | 2003-12-18 | — | — | US | disclosed |
| US-3956241-A | CHROMIUM(III) CHELATE COMPOUND | AEROJET-GENERAL CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232994-A1 | Bicyclic thiophene derivatives and combinatorial libraries thereof | CXCR2, BICRA, CXCR1 | BCAT2 659/4885ALDH1A1 928/4885MAPT 2743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.