SCHEMBL8477209

SCHEMBL8477209

CC(=O)NC(=O)c1ccccc1C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.47
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPT P10636 2/20 0.47
HPGD P15428 2/20 0.47
TSHR P16473 2/20 0.47
HSD17B10 Q99714 1/20 0.47
POLB P06746 1/20 0.46
METAP2 P50579 1/20 0.44
BCAT2 O15382 1/20 0.42
IRAK4 Q9NWZ3 1/20 0.42
PTK2 Q05397 1/20 0.41
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CRBN Q96SW2 1/20 0.39
LMNA P02545 1/20 0.39
NPC1 O15118 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17766647 0.87 ALDH1A1 (0.54) SIRT2ALDH1A1KDM4EMAPTHPGD
SCHEMBL7093583 0.82 BCAT2 (0.48) SIRT2ALDH1A1KDM4EMAPTHPGD
SCHEMBL6999516 0.80 ALDH1A1 (0.55) ALDH1A1KDM4EMAPTHPGDHSD17B10
SCHEMBL4666198 0.79 GAA (0.59) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL30064209 0.79 GAA (0.59) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL11411919 0.78 ALDH1A1 (0.58) SIRT2ALDH1A1KDM4EMAPTHPGD
SCHEMBL29067150 0.78 TSHR (0.54) ALDH1A1KDM4EMAPTHPGDTSHR
SCHEMBL29191662 0.78 SMN1; SMN2 (0.62) ALDH1A1KDM4EMAPTHPGDPOLB
Salacetamide SCHEMBL25410 0.78 KDM4E (0.61) ALDH1A1KDM4EMAPTHPGDTSHR
Hydrochloric Acid SCHEMBL30576696 0.78 GAA (0.57) ALDH1A1KDM4EMAPTHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5985815-A Bleach activators WARWICK INTERNATIONAL GROUP LIMITED (GB) 1999-11-16 US disclosed
EP-0730632-B1 BLEACH ACTIVATORS WARWICK INT GROUP (GB) 1998-03-18 EP disclosed