SCHEMBL7093595

SCHEMBL7093595

CCCCCCc1c(C(=O)O)ccc2cc(C(=O)O)ccc12

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.50
PPARA Q07869 2/20 0.48
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
RARA P10276 1/20 0.47
MAPT P10636 1/20 0.47
MTOR P42345 1/20 0.47
KMT2A Q03164 1/20 0.47
PTPN1 P18031 1/20 0.47
PLK1 P53350 7/20 0.46
PLK3 Q9H4B4 2/20 0.46
PTPN11 Q06124 1/20 0.45
PPARG P37231 1/20 0.45
KAT8 Q9H7Z6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4945605 0.86 PPARA (0.51) RARBPPARAMEN1RARAMAPT
SCHEMBL28217927 0.83 PLA2G4A (0.41) RARBPPARAMEN1ALDH1A1MAPT
SCHEMBL3157876 0.82 WDR5 (0.50) RARBPPARAPLK1PPARGKAT8
SCHEMBL4078780 0.81 PTPN1 (0.53) PTPN1PTPN11
SCHEMBL5668303 0.81 PTPN1 (0.43) ALDH1A1PTPN1
SCHEMBL29038628 0.81 CA12 (0.43) MEN1ALDH1A1MAPTKMT2A
SCHEMBL11115871 0.80 WDR5 (0.51) RARBPPARAALDH1A1
SCHEMBL28496833 0.79 RARB (0.49) RARBPPARAMEN1ALDH1A1RARA
SCHEMBL5666986 0.79 PTPN1 (0.44) MEN1KMT2APTPN1PPARG
SCHEMBL18543774 0.79 RARB (0.49) RARBPPARAMEN1ALDH1A1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003084496-A1 LIGHT-PROTECTIVE PREPARATIONS CONTAINING A PHOTOSTABLE UV-A FILTER SYMRISE GMBH & CO. KG (DE) 2003-10-16 WO claimed