Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 7/20 | 0.38 |
| ▸ | HTR7 | P34969 | 6/20 | 0.38 |
| ▸ | HTR6 | P50406 | 5/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24410388 | 0.78 | DRD2 (0.47) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL2774476 | 0.78 | ACHE (0.42) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL19141702 | 0.78 | ACHE (0.42) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL5450472 | 0.75 | DRD2 (0.43) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL19142287 | 0.74 | MAPT (0.39) | ACHEDRD2SLC6A4HTR2AHTR7 | |
| SCHEMBL8116328 | 0.73 | MAPT (0.56) | ACHEDRD2HTR2AHTR7HTR6 | |
| SCHEMBL8249064 | 0.73 | DRD2 (0.47) | DRD2SLC6A4HTR2AHTR7HTR6 | |
| SCHEMBL5407608 | 0.73 | DRD2 (0.47) | DRD2HTR2AHTR7HTR6 | |
| SCHEMBL15266105 | 0.73 | HTR2A (0.47) | DRD2HTR2AHTR7HTR6HTR1A | |
| SCHEMBL7539608 | 0.73 | DRD2 (0.47) | DRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | claimed |