Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971201 | 0.83 | ALDH1A1 (0.47) | ALDH1A1GAATSHRSMN1; SMN2MAPT | |
| SCHEMBL11824385 | 0.77 | KCNA3 (0.50) | ALDH1A1GAATSHRSMN1; SMN2MAPT | |
| SCHEMBL4631291 | 0.77 | TACR1 (0.56) | OPRM1SLC6A4KCNH2 | |
| SCHEMBL11819540 | 0.76 | DPP4 (0.42) | ALDH1A1GAATSHRSMN1; SMN2MAPT | |
| SCHEMBL11819537 | 0.76 | DPP4 (0.42) | ALDH1A1GAATSHRSMN1; SMN2MAPT | |
| SCHEMBL11821600 | 0.76 | DPP4 (0.42) | ALDH1A1GAATSHRSMN1; SMN2MAPT | |
| SCHEMBL7088572 | 0.76 | MAOA (0.42) | ALDH1A1GAATSHRSMN1; SMN2MAPT | |
| SCHEMBL10880933 | 0.76 | ALDH1A1 (0.46) | ALDH1A1GAATSHRSMN1; SMN2MAPT | |
| SCHEMBL1357048 | 0.75 | GAA (0.39) | ALDH1A1GAATSHRMAPTCHRM5 | |
| SCHEMBL11090978 | 0.74 | DPP4 (0.47) | CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6653486-B2 | Photopolymerizable; vinyl ether, photoinitiator, iodinium salt, and visible light sensitizer; dentistry, adhesives | CURATORS OF THE UNIVERSITY OF MISSOURI | 2003-11-25 | — | — | US | disclosed |
| US-20030119931-A1 | Novel spiroorthocarbonates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2003-06-26 | — | — | US | disclosed |
| US-6458865-B2 | FOR DENTAL RESTORATION MATERIAL | CURATORS OF THE UNIVERSITY OF MISSOURI | 2002-10-01 | — | — | US | disclosed |
| US-20020013380-A1 | PHOTOPOLYMERIZABLE VINYL ETHER BASED MONOMERIC FORMULATIONS AND POLYMERIZABLE COMPOSITIONS WHICH MAY INCLUDE CERTAIN NOVEL SPIROORTHOCARBONATES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-01-31 | — | — | US | disclosed |