Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.38 |
| ▸ | KDR | P35968 | 6/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.38 |
| ▸ | AURKA | O14965 | 3/20 | 0.38 |
| ▸ | RET | P07949 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.38 |
| ▸ | STK3 | Q13188 | 2/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | GAK | O14976 | 1/20 | 0.38 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7093846 | 1.00 | FLT1 (0.40) | FLT1FGFR1KDRPDGFRBAURKA | |
| SCHEMBL7636123 | 0.86 | GAA (0.39) | FFAR1THRATHRBRXRARXRB | |
| SCHEMBL7090165 | 0.80 | ERBB2 (0.41) | NTRK1ROS1FERSLKERBB2 | |
| SCHEMBL7090167 | 0.80 | ERBB2 (0.41) | NTRK1ROS1FERSLKERBB2 | |
| SCHEMBL7094724 | 0.79 | MAPT (0.41) | THRATHRBRXRARXRBRXRG | |
| SCHEMBL7094725 | 0.79 | MAPT (0.41) | THRATHRBRXRARXRBRXRG | |
| SCHEMBL8196580 | 0.79 | PTPN1 (0.43) | FFAR1MAOAMAOBTHRATHRB | |
| SCHEMBL7089048 | 0.77 | ERBB2 (0.43) | CSNK1DSLKERBB2EGFRIGF1R | |
| SCHEMBL7089049 | 0.77 | ERBB2 (0.43) | CSNK1DSLKERBB2EGFRIGF1R | |
| SCHEMBL7636730 | 0.74 | PTPN1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030121113-A1 | Oxobenzofuranylide-dihydroindolone | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| US-6503937-B1 | Coloring agents for high molecular weight materials such as polymers | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-01-07 | — | — | US | disclosed |
| EP-1123289-B1 | OXOBENZOFURANYLIDE-DIHYDROINDOLONES | CIBA SC HOLDING AG (CH) | 2002-11-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030121113-A1 | Oxobenzofuranylide-dihydroindolone | CYP1B1, CYP1A1, ECI1 | FLT1 4815/4885FGFR1 2501/4885KDR 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.