SCHEMBL708944

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL707714	0.85	LPAR1 (0.51)	LPAR1LPAR3PSEN1PSEN2APH1B
	SCHEMBL707824	0.84	LPAR1 (0.52)	LPAR1PPARG
	SCHEMBL706891	0.82	KMT2A (0.42)	POLBKDM4ECCR9MEN1KMT2A
	SCHEMBL707717	0.80	SLC6A2 (0.47)	LPAR1KDM4EKMT2AMTNR1AMTNR1B
	SCHEMBL706447	0.79	LPAR1 (0.52)	LPAR1POLBKDM4EMEN1KMT2A
	SCHEMBL705825	0.77	SRD5A2 (0.57)	POLBKDM4EMEN1KMT2A
	SCHEMBL709317	0.76	MCL1 (0.47)	POLBKDM4EMEN1KMT2AMCL1
	SCHEMBL709389	0.75	PSEN1 (0.55)	LPAR1LPAR3PSEN1PSEN2APH1B
	SCHEMBL709318	0.73	PLA2G4A (0.45)	PSEN1PSEN2APH1BNCSTNAPH1A
	SCHEMBL13851461	0.71	HTT (0.67)	LPAR1LPAR3POLBKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.