Valomaciclovir Stearate

Valomaciclovir Stearate

SCHEMBL709408

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](CCOC(=O)[C@@H](N)C(C)C)Cn1cnc2c(=O)[nH]c(N)nc21

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
HBB P68871 2/20 0.58
MAPK1 P28482 1/20 0.58
PDE3A Q14432 1/20 0.54
HPRT1 P00492 15/20 0.47
USP2 O75604 1/20 0.42
PNP P00491 1/20 0.42
TSHR P16473 1/20 0.42
EDNRA P25101 1/20 0.42
HTR2A P28223 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL712944 1.00 MEN1 (0.59) MEN1KMT2AHBBMAPK1PDE3A
SCHEMBL712561 1.00 MEN1 (0.59) MEN1KMT2AHBBMAPK1PDE3A
Valomaciclovir Stearate SCHEMBL709409 1.00 MEN1 (0.59) MEN1KMT2AHBBMAPK1PDE3A
SCHEMBL712945 1.00 MEN1 (0.59) MEN1KMT2AHBBMAPK1PDE3A
SCHEMBL710743 1.00 MEN1 (0.59) MEN1KMT2AHBBMAPK1PDE3A
SCHEMBL712223 1.00 MEN1 (0.59) MEN1KMT2AHBBMAPK1PDE3A
SCHEMBL710633 1.00 MEN1 (0.59) MEN1KMT2AHBBMAPK1PDE3A
SCHEMBL712562 1.00 MEN1 (0.59) MEN1KMT2AHBBMAPK1PDE3A
SCHEMBL708847 1.00 MEN1 (0.59) MEN1KMT2AHBBMAPK1PDE3A
SCHEMBL712943 1.00 MEN1 (0.59) MEN1KMT2AHBBMAPK1PDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024118480-A1 USE OF ANTIVIRAL AGENTS, COMPOSITION OF MATTER, COMBINATION PREPARATIONS/AGENTS TO TREAT CHRONIC DISEASES ASSOCIATED WITH EPSTEIN-BARR VIRUS AND OTHER HUMAN HERPES VIRUSES EPIPHANY BIOSCIENCES (US) 2024-06-06 WO claimed
US-20160346287-A1 METHOD OF TREATING VIRAL INFECTIONS EPIPHANY BIOSCIENCES, INC. 2016-12-01 US claimed
US-20150050241-A1 METHOD OF TREATING VIRAL INFECTIONS EPIPHANY BIOSCIENCES, INC. 2015-02-19 US claimed
WO-2014047562-A2 METHOD OF TREATING AND/OR PREVENTING SHINGLES AND METHOD OF TREATING AND/OR PREVENTING ZOSTER ASSOCIATED PAIN EPIPHANY BIOSCIENCES (US) 2014-03-27 WO claimed
US-8124609-B2 Acyclic nucleoside derivatives MEDIVIR AB (SE) 2012-02-28 US claimed
WO-2011022712-A1 METHOD OF TREATING INFECTIOUS MONONUCLEOSIS WITH ACYLIC NUCLEOSIDE DERIVATIVES EPIPHANY BIOSCIENCES, INC. (US) 2011-02-24 WO claimed
US-7517992-B2 Non-nucleoside reverse transcriptase inhibitors MEDIVIR AB (SE) 2009-04-14 US claimed
US-20090076041-A1 ACYCLIC NUCLEOSIDE DERIVATIVES MEDIVIR AB (SE) 2009-03-19 US claimed
US-7432274-B2 Acyclic nucleoside derivatives MEDIVIR AB (SE) 2008-10-07 US claimed
US-20040132749-A1 Acyclic nucleoside derivatives MEDIVIR AB (SE) 2004-07-08 US claimed
US-6703394-B2 VIRICIDES SUCH AS (R)-9-(2-(STEAROYLOXYMETHYL)-4-(L-VALYLOXY) BUTYL)GUANINE FOR TREATMENT OF HIV; BIOAVAILABILITY MEDIVIR AB (SE) 2004-03-09 US claimed
EP-0888348-B1 ACYCLIC NUCLEOSIDE DERIVATIVES MEDIVIR AB (SE) 2003-01-22 EP claimed
US-20020188125-A1 Acyclic nucleoside derivatives MEDIVIR AB 2002-12-12 US claimed
US-6255312-B1 VIRICIDES MEDIVIR AB (SE) 2001-07-03 US claimed
EP-0888348-A1 ACYCLIC NUCLEOSIDE DERIVATIVES Medivir Aktiebolag (SE) 1999-01-07 EP claimed
WO-1997030051-A1 ACYCLIC NUCLEOSIDE DERIVATIVES MEDIVIR AB (SE) 1997-08-21 WO claimed
US-12485088-B2 Rapidly-orodispersible tablets having an interior cavity Aprecia Pharmaceuticals LLC (US) 2025-12-02 US disclosed
US-20250339502-A1 RIBONUCLEASES FOR TREATING VIRAL INFECTIONS ORGENESIS INC. (US) 2025-11-06 US disclosed
WO-1997030051-A1 ACYCLIC NUCLEOSIDE DERIVATIVES MEDIVIR AB (SE) 1997-08-21 WO disclosed
WO-1997030052-A1 SYNTHESIS OF ACYCLIC NUCLEOSIDES MEDIVIR AB (SE) 1997-08-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160346287-A1 METHOD OF TREATING VIRAL INFECTIONS IFNG, BCL9, GDA MEN1 74/4885KMT2A 1025/4885HBB 412/4885
US-20090076041-A1 ACYCLIC NUCLEOSIDE DERIVATIVES NUDT1, PNP, NSUN2 MEN1 1917/4885KMT2A 2396/4885HBB 1470/4885
US-20150050241-A1 METHOD OF TREATING VIRAL INFECTIONS IFNG, BCL9, GDA MEN1 74/4885KMT2A 1025/4885HBB 412/4885
US-20040132749-A1 Acyclic nucleoside derivatives NSUN2, NUDT1, PNP MEN1 2312/4885KMT2A 2483/4885HBB 1773/4885
US-20020188125-A1 Acyclic nucleoside derivatives NSUN2, NUDT1, PNP MEN1 2510/4885KMT2A 2354/4885HBB 1623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.