Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.77 |
| ▸ | FBP1 | P09467 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7089169 | 0.99 | EGFR (0.76) | EGFRFBP1 | |
| SCHEMBL7092567 | 0.97 | EGFR (0.72) | EGFRFBP1 | |
| SCHEMBL7090058 | 0.94 | EGFR (0.69) | EGFRFBP1 | |
| SCHEMBL7089292 | 0.93 | EGFR (0.67) | EGFRFBP1 | |
| SCHEMBL7093305 | 0.87 | EGFR (1.00) | EGFRFBP1 | |
| SCHEMBL7088581 | 0.86 | EGFR (0.81) | EGFRFBP1 | |
| SCHEMBL7093775 | 0.86 | EGFR (0.58) | EGFR | |
| SCHEMBL7089342 | 0.86 | EGFR (0.64) | EGFRFBP1 | |
| SCHEMBL4315736 | 0.85 | EGFR (0.79) | EGFRFBP1 | |
| SCHEMBL6234224 | 0.85 | EGFR (1.00) | EGFRFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | BAUER PAUL H (US) | 2003-07-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144308-A1 | Fructose 1,6-bisphosphatase inhibitors | FBP1, HK1, G6PC1 | EGFR 2906/4885FBP1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.