Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094666 | 1.00 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2HTR1A | |
| SCHEMBL7094661 | 1.00 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2HTR1A | |
| SCHEMBL7094658 | 0.81 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3154482 | 0.73 | SLC6A3 (0.59) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL3158646 | 0.73 | SLC6A3 (0.59) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL3155658 | 0.73 | SLC6A3 (0.59) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL3158503 | 0.73 | SLC6A3 (0.59) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL3155661 | 0.73 | SLC6A3 (0.59) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| Bromide SCHEMBL3155630 | 0.72 | SLC6A3 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| Bromide SCHEMBL3155634 | 0.72 | SLC6A3 (0.58) | SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981515-B1 | PIPERIDINE DERIVATIVES AS NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2003-08-27 | — | — | EP | claimed |
| US-6376673-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | NEUROSEARCH A/S (DK) | 2002-04-23 | — | — | US | claimed |
| EP-0981515-B1 | PIPERIDINE DERIVATIVES AS NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2003-08-27 | — | — | EP | disclosed |
| US-6376673-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | NEUROSEARCH A/S (DK) | 2002-04-23 | — | — | US | disclosed |
| EP-0981515-A1 | PIPERIDINE DERIVATIVES AS NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998051668-A1 | PIPERIDINE DERIVATIVES AS NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 1998-11-19 | — | — | WO | disclosed |