Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079936 | 0.84 | SLC6A3 (0.56) | SLC6A3 | |
| SCHEMBL7079941 | 0.84 | SLC6A3 (0.56) | SLC6A3 | |
| SCHEMBL7800963 | 0.84 | SLC6A3 (0.56) | SLC6A3 | |
| SCHEMBL7079939 | 0.84 | SLC6A3 (0.56) | SLC6A3 | |
| SCHEMBL7094661 | 0.81 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL7094666 | 0.81 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL7094662 | 0.81 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL13979388 | 0.80 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13594763 | 0.78 | — | — | |
| SCHEMBL14224128 | 0.78 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981515-B1 | PIPERIDINE DERIVATIVES AS NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH AS (DK) | 2003-08-27 | — | — | EP | disclosed |
| US-6376673-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | NEUROSEARCH A/S (DK) | 2002-04-23 | — | — | US | disclosed |
| EP-0981515-A1 | PIPERIDINE DERIVATIVES AS NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2000-03-01 | — | — | EP | disclosed |
| WO-1998051668-A1 | PIPERIDINE DERIVATIVES AS NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 1998-11-19 | — | — | WO | disclosed |