Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27587659 | 0.80 | GRM2 (0.39) | GRM2GRM3 | |
| SCHEMBL15565360 | 0.75 | ABCC4 (0.39) | TSHR | |
| SCHEMBL7470248 | 0.75 | GRM2 (0.34) | GRM2GRM3 | |
| SCHEMBL31147030 | 0.74 | TSHR (0.36) | GRM2GRM3TSHR | |
| SCHEMBL16892927 | 0.73 | CA2 (0.36) | GRM2GRM3 | |
| SCHEMBL2139826 | 0.71 | GRM2 (0.39) | GRM2GRM3TSHR | |
| Trifluoroacetic Acid SCHEMBL6890645 | 0.71 | GRM2 (0.36) | GRM2GRM3 | |
| SCHEMBL28426903 | 0.69 | GRM2 (0.32) | GRM2GRM3 | |
| SCHEMBL28886364 | 0.69 | GRM2 (0.35) | GRM2GRM3 | |
| SCHEMBL30873728 | 0.68 | MMP8 (0.32) | GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |