Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.62 |
| ▸ | CES2 | O00748 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29420172 | 0.84 | CES1 (0.65) | CES1CES2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1140280 | 0.84 | CES1 (0.65) | CES1CES2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9853534 | 0.81 | TDP1 (0.49) | CES1CES2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16690236 | 0.79 | POLB (0.63) | CES1CES2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9670443 | 0.79 | CES1 (0.74) | CES1CES2ALDH1A1LMNATDP1 | |
| SCHEMBL28930611 | 0.79 | CES1 (0.74) | CES1CES2ALDH1A1LMNATDP1 | |
| SCHEMBL28949248 | 0.79 | CES1 (0.74) | CES1CES2ALDH1A1LMNATDP1 | |
| SCHEMBL23466337 | 0.79 | CES1 (0.58) | CES1CES2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5609313 | 0.79 | CES2 (0.58) | CES1CES2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16089348 | 0.78 | BLM (0.43) | CES1CES2ALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158237-A1 | Combination of antioxidant substances for the treatment of alzheimer's disease | COLBA R & D INC. (CA) | 2003-08-21 | — | — | US | disclosed |