SCHEMBL7095382

SCHEMBL7095382

Cc1ccc(S(=O)(=O)NCCCCN2C(=O)c3ccccc3C2=O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.58
ALDH1A1 P00352 7/20 0.56
MBTD1 Q05BQ5 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CA12 O43570 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
HTR2A P28223 1/20 0.52
SLC6A4 P31645 1/20 0.52
HTR7 P34969 1/20 0.52
HTR2B P41595 1/20 0.52
KCNH2 Q12809 1/20 0.52
ALOX15 P16050 1/20 0.51
LMNA P02545 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
LPAR2 Q9HBW0 2/20 0.50
GAA P10253 1/20 0.50
MAPK1 P28482 1/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7094855 0.96 L3MBTL1 (0.59) HTR1AALDH1A1MBTD1L3MBTL1CA12
SCHEMBL29163155 0.86 ALDH1A1 (0.64) HTR1AALDH1A1HTR2AHTR7MEN1
SCHEMBL30486840 0.86 ALDH1A1 (0.64) HTR1AALDH1A1HTR2AHTR7MEN1
SCHEMBL7094852 0.81 ALDH1A1 (0.79) ALDH1A1MBTD1L3MBTL1CA12CA2
SCHEMBL7095193 0.79 ALDH1A1 (0.77) ALDH1A1MBTD1L3MBTL1CA12CA2
SCHEMBL7092896 0.79 ALDH1A1 (0.77) ALDH1A1MBTD1L3MBTL1CA12CA2
SCHEMBL7093365 0.79 ALDH1A1 (0.77) ALDH1A1MBTD1L3MBTL1CA12CA2
SCHEMBL7095731 0.79 ALDH1A1 (0.77) ALDH1A1MBTD1L3MBTL1CA12CA2
SCHEMBL7097551 0.79 ALDH1A1 (0.77) ALDH1A1MBTD1L3MBTL1CA12CA2
SCHEMBL7095949 0.79 ALDH1A1 (0.77) ALDH1A1MBTD1L3MBTL1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6627399-B1 Using compound of given formula as accelerator RIKEN (JP) 2003-09-30 US disclosed
US-20030073202-A1 RNA polymerase transcription promoter and nucleic acid sequencing method IWATA MASAAKI (JP) 2003-04-17 US disclosed
EP-1061130-A1 RNA POLYMERASE TRANSCRIPTION PROMOTERS AND METHOD FOR DETERMINING BASE SEQUENCE Riken (JP) 2000-12-20 EP disclosed