Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190527 | 0.79 | KDM4E (0.46) | ALDH1A1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL9581 | 0.73 | — | — | |
| SCHEMBL8154900 | 0.68 | ABCG2 (0.47) | LMNAKMT2A | |
| SCHEMBL23143295 | 0.67 | PDGFRB (0.43) | ALDH1A1KDM4E | |
| SCHEMBL15549237 | 0.67 | ALDH1A1 (0.35) | ALDH1A1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL5758003 | 0.67 | — | — | |
| SCHEMBL5294327 | 0.66 | HPGD (0.34) | ALDH1A1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL5755357 | 0.65 | PIK3CA (0.36) | ALDH1A1KDM4E | |
| SCHEMBL4329849 | 0.64 | HTR2C (0.43) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8168648 | 0.64 | CYP19A1 (0.44) | ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165566-B1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE AS INHIBITORS OF CYTOKINE MEDIATED DISEASE | ASTRAZENECA AB (SE) | 2003-08-20 | — | — | EP | claimed |