⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763542 | 0.74 | PDE5A (0.57) | — | |
| SCHEMBL7095463 | 0.73 | NUDT1 (0.33) | — | |
| SCHEMBL7977958 | 0.68 | NUDT1 (0.46) | — | |
| SCHEMBL5512822 | 0.67 | — | — | |
| SCHEMBL1170747 | 0.67 | METAP1 (0.72) | — | |
| SCHEMBL2862 | 0.65 | — | — | |
| SCHEMBL83269 | 0.65 | — | — | |
| SCHEMBL9217 | 0.65 | — | — | |
| SCHEMBL9384243 | 0.64 | PARP1 (0.44) | — | |
| SCHEMBL12396542 | 0.64 | PARP1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3243 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373809-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | Novartis AG (CH) | 2024-05-29 | — | — | EP | claimed |
| WO-2024106781-A1 | LIPID COMPOUND AND COMPOSITION FOR DELIVERY OF ACTIVE SUBSTANCE | 한국생명공학연구원 | 2024-05-23 | — | — | WO | claimed |
| US-11987588-B2 | Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of heart failure and disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2024-05-21 | — | — | US | claimed |
| US-20240147840-A1 | SPIROFLUORENE SILICON COMPOUND AND ELECTROLUMINESCENCE USING THE SAME | Shanghai Tianma Micro-electronics Co., Ltd. (CN) | 2024-05-02 | — | — | US | claimed |
| CN-117836296-A | Pyrazolopyridone compounds | 百济神州有限公司 | 2024-04-05 | — | — | CN | claimed |
| EP-4076734-B1 | COMPOSITE MATERIAL COMBINING MOF NANOPARTICLES AND METAL NANOPARTICLES | CENTRE NAT RECH SCIENT (FR) | 2024-04-03 | — | — | EP | claimed |
| US-20240059675-A1 | PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-02-22 | — | — | US | claimed |
| WO-2024028245-A1 | PIPERIDINYLPYRIDINYLCARBONITRILE DERIVATIVES AS INHIBITORS OF GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE AND GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE LIKE PROTEIN | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-02-08 | — | — | WO | claimed |
| US-20230331725-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS, INC. | 2023-10-19 | — | — | US | claimed |
| EP-3445762-B1 | SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2023-09-13 | — | — | EP | claimed |
| EP-0748805-B1 | Naphthalene derivatives, process for the preparation thereof, and intermediates therefor, and pharmaceutical compositions comprising them | TANABE SEIYAKU CO (JP) | 1998-04-08 | — | — | EP | claimed |
| US-5580863-A | TREATMENT OF OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-03 | — | — | US | claimed |
| US-5459147-A | Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma | DR. KARL THOMAE GMBH (DE) | 1995-10-17 | — | — | US | claimed |
| US-5444066-A | Thioformamide derivatives having hypotensive activity | EISAI CO., LTD. (JP) | 1995-08-22 | — | — | US | claimed |
| EP-0609442-A1 | THIOFORMAMIDE DERIVATIVE | Eisai Co., Ltd. (JP) | 1994-08-10 | — | — | EP | claimed |
| EP-0581166-A1 | Benzimidazoles, process for their preparation and their use as angiotensin-II antagonists | Dr. Karl Thomae GmbH (DE) | 1994-02-02 | — | — | EP | claimed |
| EP-0560330-A2 | Substituted benzimidazolyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-09-15 | — | — | EP | claimed |
| EP-0556789-A2 | Substituted biphenyl derivatives, therapeutic agents containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-08-25 | — | — | EP | claimed |
| EP-0222283-B1 | AMINO-ACID DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-12-30 | — | — | EP | claimed |
| EP-0502314-A1 | Benzimidazol, medicaments containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-09 | — | — | EP | claimed |