Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5773506 | 0.85 | PTPN1 (0.47) | CNR1CNR2HDAC1HDAC2LMNA | |
| SCHEMBL7211425 | 0.76 | L3MBTL1 (0.39) | CNR1CNR2HDAC1HDAC2LMNA | |
| SCHEMBL7539805 | 0.73 | NPC1 (0.42) | LMNASMN1; SMN2BCHEACHEMEN1 | |
| SCHEMBL5770319 | 0.72 | CHRM1 (0.47) | KLKB1BCHEACHECHRM1 | |
| SCHEMBL7536570 | 0.72 | ALDH1A1 (0.36) | LMNAKLKB1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7535029 | 0.71 | GAA (0.42) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL5769433 | 0.70 | PTPN1 (0.53) | CNR1CNR2HDAC1HDAC2LMNA | |
| SCHEMBL5770569 | 0.70 | PTPN1 (0.53) | CNR1CNR2HDAC1HDAC2LMNA | |
| SCHEMBL7558300 | 0.70 | KMT2A (0.42) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL7553313 | 0.68 | KDM4E (0.43) | HDAC1HDAC2LMNAACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301516-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2003-04-16 | — | — | EP | disclosed |