Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18400025 | 0.90 | TP53 (0.46) | TP53RAB9AKDM4EP2RX1P2RX4 | |
| SCHEMBL7098229 | 0.89 | EPHX2 (0.38) | KMT2ARAB9AP2RX1RXFP1SMN1; SMN2 | |
| SCHEMBL13612670 | 0.87 | TP53 (0.39) | KMT2ATP53PTGESRAB9ARXFP1 | |
| SCHEMBL15019905 | 0.86 | TP53 (0.43) | TP53PTGESRAB9AKDM4ERXFP1 | |
| SCHEMBL29372876 | 0.86 | TP53 (0.43) | TP53PTGESRAB9AKDM4ERXFP1 | |
| SCHEMBL29733636 | 0.86 | TP53 (0.43) | TP53PTGESRAB9AKDM4ERXFP1 | |
| SCHEMBL13612668 | 0.84 | TP53 (0.36) | TP53PTGESRAB9ARXFP1SMN1; SMN2 | |
| SCHEMBL29175564 | 0.82 | TP53 (0.43) | TP53RAB9AKDM4EP2RX1P2RX4 | |
| SCHEMBL861380 | 0.82 | ALDH1A1 (0.42) | TP53PTGESRAB9AP2RX1RXFP1 | |
| SCHEMBL13612669 | 0.82 | CCR8 (0.36) | TP53PTGESRXFP1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642379-B1 | Containing oxazolyl, thiazolyl or imidazolyl groups | NIHON NOHYAKU CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| EP-1195375-B1 | BENZAMIDE DERIVATIVES, INSECTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE AND USAGE THEREOF | NIHON NOHYAKU CO LTD (JP) | 2003-08-27 | — | — | EP | disclosed |
| EP-1195375-A1 | BENZAMIDE DERIVATIVES, INSECTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE AND USAGE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2002-04-10 | — | — | EP | disclosed |